Description:

Size: 100 microliters

Catalog no.: GENTObs-12413R-A594

Price: 489 EUR

Product details

Subcellular locations

N/A

Swiss Prot

N/A

Gene ID

4052

Modification site

None

Target Protein/Peptide

LTBP1

Applications

IF(IHC-P)

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Conjugated with

ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Clonality

Polyclonal Antibody

Clone

Polyclonal Antibodies

Other name

Anti-LTBP1 Polyclonal

Purification method

Purified by Protein A.

Also known as

LTBP1 Polyclonal Antibody

Group

Polyclonals and antibodies

Type

Conjugated Primary Antibody

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host organism

Rabbit (Oryctolagus cuniculus)

Properties

For facs or microscopy Alexa 1 conjugate.

Specificity

This antibody reacts specifically with LTBP1

Modification

No modification has been applied to this antibody

Antigen Source

KLH conjugated synthetic peptide derived from human LTBP1

Cross reactive species

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Synonyms

9430031G15Rik; 9830146M04; Latent transforming growth factor beta binding protein 1; Latent-transforming growth factor beta-binding protein 1; Latent-transforming growth factor beta-binding protein, isoform 1L; Latent-transforming growth factor beta-binding protein, isoform 1S; LBT1S; LTBP-1; Ltbp1; LTBP1_HUMAN; MGC163161; TGF-beta1-BP-1; Tgfb; Transforming growth factor beta-1-binding protein 1; Transforming growth factor beta-1-masking protein large subunit.

Background information

Latent transforming growth factor-beta 1 binding protein 1 (LTBP-1), a heavy glycoprotein, is part of the platelet-derived TGF-beta 1 complex. LTBP-1 serves as an anchor for latent TGF-beta in the extracellular matrix and is a component of microfibrillar structures. Cleavage of LTBP results in LTBP-1, which may sequester latent TGF-beta in the extracellular matrix and regulate its activation. LTBP-1 mRNA is enriched in ovarian carcinoma tissues and highly expressed in serous and mucinous adenocarcinomas.