Description:

Size: 100 microliters

Catalog no.: GENTObs-8433R-A594

Price: 489 EUR

Product details

Swiss Prot

N/A

Modification site

None

Target Protein/Peptide

BTNL8

Gene ID

79908

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Subcellular locations

Extracellular

Applications

FCM, IF(IHC-P)

Conjugated

Alexa conjugate 1

Conjugated with

ALEXA FLUOR® 594

Clonality

Polyclonal Antibody

Cross reactive species

Human (Homo sapiens)

Clone

Polyclonal Antibodies

Other name

Anti-BTNL8 Polyclonal

Purification method

Purified by Protein A.

Also known as

BTNL8 Polyclonal Antibody

Group

Polyclonals and antibodies

Type

Conjugated Primary Antibody

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host organism

Rabbit (Oryctolagus cuniculus)

Applications with corresponding dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200)

Properties

For facs or microscopy Alexa 1 conjugate.

Specificity

This antibody reacts specifically with BTNL8

Modification

No modification has been applied to this antibody

Antigen Source

KLH conjugated synthetic peptide derived from human BTNL8

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Synonyms

B7 H5 costimulatory molecule; Butyrophilin like 8; Butyrophilin like protein 8; butyrophilin-like 8; FLJ21458; FLJ51528; MGC149619; BTNL8_HUMAN.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Background information

BTNL8 is a 500 amino acid single-pass type I membrane protein that belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and one Ig-like V-type (immunoglobulin-like) domain. Expressed as multiple alternatively spliced isoforms, BTNL8 is encoded by a gene which maps to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 comprises about 6% of human genomic DNA. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm on chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.