Description:

    Size: 100 microliters

    Catalog no.: GENTObs-7554R-A594

    Price: 516 EUR

    Product details

    Swiss Prot

    N/A

    Gene ID

    1969

    Subcellular locations

    Cytoplasm

    Applications

    IF(IHC-P)

    Concentration

    1ug per 1ul

    Excitation emission

    590nm/617nm

    Modification

    Phosphorylation

    Conjugated

    Alexa conjugate 1

    Conjugated with

    ALEXA FLUOR® 594

    Modification site

    Tyr588 (A3 Tyr596)

    Applications with corresponding dilutions

    IF(IHC-P)(1:50-200)

    Clonality

    Polyclonal Antibody

    Clone

    Polyclonal Antibodies

    Purification method

    Purified by Protein A.

    Type

    Conjugated Primary Antibody

    Conjugation

    Alexa Fluor,ALEXA FLUOR® 594

    Host organism

    Rabbit (Oryctolagus cuniculus)

    Target Protein/Peptide

    Eph receptor A2/A3 Tyr588/Tyr596

    Other name

    Anti-Eph receptor A2+A3 (Y588/Y596)

    Also known as

    Eph receptor A2+A3 (Y588/Y596) Antibody

    Properties

    For facs or microscopy Alexa 1 conjugate.

    Cross reactive species

    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

    Specificity

    This antibody reacts specifically with Eph receptor A2+A3 (Y588/Y596)

    Storage

    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

    Antigen Source

    KLH conjugated synthetic phosphopeptide derived from human Eph receptor A2 around the phosphorylation site of Tyr588

    Cross Reactive Species details

    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

    Synonyms

    Eph receptor A2+A3 phospho Y588 + Y596 ECK; EPH Receptor A2; EPH Receptor A3; EPHA2; EPHA3; Ephrin type A receptor 2; Ephrin type A receptor 3; Epithelial cell kinase; ETK; ETK1; HEK; Tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor ETK1.

    Advisory

    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

    Background information

    Eph receptor A2 is the receptor for members of the ephrin-A family. It binds to ephrin-A1, -A3, -A4 and -A5. Eph receptor A3 is also a receptor for members of the ephrin-A family. It binds to ephrin-A2, -A3, -A4 and -A5 and is thought to play a role in lymphoid function. Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5. It binds more poorly to ephrin-A2 and -A3. It may play a role in a signal transduction process involved in hindbrain pattern formation.

    Description

    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.