Description:

    Size: 100 microliters

    Catalog no.: GENTObs-2327R-A594

    Price: 489 EUR

    Product details

    Swiss Prot

    N/A

    Gene ID

    N/A

    Virus

    hbv

    Subcellular locations

    N/A

    Modification site

    None

    Cross reactive species

    Virus

    Applications

    IF(IHC-P)

    Excitation emission

    590nm/617nm

    Concentration

    1ug per 1ul

    Conjugated

    Alexa conjugate 1

    Conjugated with

    ALEXA FLUOR® 594

    Clonality

    Polyclonal Antibody

    Applications with corresponding dilutions

    IF(IHC-P)(1:50-200)

    Target Protein/Peptide

    HBV pre S1/S2 protein

    Clone

    Polyclonal Antibodies

    Purification method

    Purified by Protein A.

    Cross Reactive Species details

    Hepatitis B virus ay/ad

    Other name

    Anti-HBV pre S1/S2 protein

    Type

    Conjugated Primary Antibody

    Conjugation

    Alexa Fluor,ALEXA FLUOR® 594

    Also known as

    HBV pre S1/S2 protein Antibody

    Host organism

    Rabbit (Oryctolagus cuniculus)

    Properties

    For facs or microscopy Alexa 1 conjugate.

    Modification

    No modification has been applied to this antibody

    Specificity

    This antibody reacts specifically with HBV pre S1/S2 protein

    Antigen Source

    KLH conjugated synthetic peptide derived from HBSAG_HBVD2 sub. ayw pre S1/S2 protein

    Storage

    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

    Synonyms

    HBSAG_HBVD2; HBSAG_HBVC5; Large envelope protein; Large surface protein; L glycoprotein; Major surface antigen; Large S protein; L-HBsAg; LHB.

    Description

    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

    Advisory

    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

    Background information

    Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.