Description:

Size: 100ul

Catalog no.: bs-1658R-A555

Price: 350 EUR

Product details

Gene ID Number

6774

Swiss Prot

P40763

Modification Site

Tyr705

French translation

anticorps

Clonality

Polyclonal

Concentration

1ug per 1ul

Immunogen range

685-725/770

Excitation emission

553nm/568nm

Target Antigen

STAT3 Tyr705

Tested applications

FCM, IF(IHC-P)

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 555

Subcellular location

Cytoplasm, Nucleus

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Crossreactivity

Human, Mouse, Rat, Pig

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200)

Also known as

Anti-STAT3 Tyr705 PAb ALEXA FLUOR 555

Specificity

This is a highly specific antibody against STAT3 Tyr705.

Long name

STAT3 (Tyr705) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3

Source

KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Tyr705

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).