Description:

    Size: 100ul

    Catalog no.: bs-3354R-A350

    Price: 350 EUR

    Product details

    Gene ID Number

    5300

    Modification Site

    Ser16

    Swiss Prot

    Q13526

    Immunogen range

    1-50/163

    French translation

    anticorps

    Tested applications

    IF(IHC-P)

    Clonality

    Polyclonal

    Target Antigen

    Pin1 Ser16

    Concentration

    1ug per 1ul

    Excitation emission

    343nm/442nm

    Modification

    Phosphorylation

    Conjugated with

    ALEXA FLUOR® 350

    Crossreactivity

    Human, Mouse, Rat

    Subcellular location

    Cytoplasm, Nucleus

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Purification

    Purified by Protein A.

    Conjugation

    Alexa Fluor,ALEXA FLUOR 350

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-Pin1 Ser16 PAb ALEXA FLUOR 350

    Specificity

    This is a highly specific antibody against Pin1 Ser16.

    Long name

    Pin1 (Ser16) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    KLH conjugated synthetic phosphopeptide derived from human Pin1 around the phosphorylation site of Ser16

    Synonyms

    DOD; UBL5; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1; PIN1

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.