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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Acetyl-Histone H4(K17) Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bs-4707R-A488

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Modification Site

K17

Gene ID Number

121504

Swiss Prot

P62805

Subcellular location

Nucleus

Immunogen range

5-40/103

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Concentration

1ug per 1ul

Excitation emission

499nm/519nm

Modification

Acetylation

Conjugation

Alexa Fluor

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Target Antigen

Acetyl-Histone H4K17

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Synonyms

H4/p; Histone H4; HIST1H4A; H4/A; H4FA

Also known as

Anti-Acetyl-Histone H4K17 PAb ALEXA FLUOR 488

Long name

Acetyl-Histone H4(K17) Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against Acetyl-Histone H4K17.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Description

N terminal acetylation or CH3CO as epigenetic regulation of Anti-Acetyl-Histone H4K17 by NATs.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acetyl-Histone H4(K17)

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Acetyl-Histone H4K17 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.