Description:

Size: 100ul

Catalog no.: bs-10743R-A594

Price: 380 EUR

Product details

Gene ID Number

834

Modification Site

None

Crossreactivity

Human

Swiss Prot

P29466

Subcellular location

Cytoplasm

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Modification

Unmodified

Immunogen range

145-170/404

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Target Antigen

Caspase-1 p20

Conjugated with

ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Caspase-1 p20 PAb ALEXA FLUOR 594

Specificity

This is a highly specific antibody against Caspase-1 p20.

Long name

Caspase-1 p20 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Caspase-1 p20

Synonyms

Caspase-1 subunit p20; Caspase-1; CASP-1; IL-1 beta-converting enzyme; Interleukin-1 beta-converting enzyme; IL1BC; IL1BCE; CASP1

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Background of the antigen

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.