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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / TRAILR2/DR5 Antibody, ALEXA FLUOR 350

Description:

Size: 100ul

Catalog no.: bs-1696R-A350

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Modification Site

None

Gene ID Number

21933

Swiss Prot

Q9QZM4

Subcellular location

Cytoplasm

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Crossreactivity

Mouse, Rat

Clonality

Polyclonal

Excitation emission

343nm/442nm

Immunogen range

330-380/381

Concentration

1ug per 1ul

Target Antigen

TRAILR2/DR5/CD262

Conjugated with

ALEXA FLUOR® 350

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-TRAILR2/DR5/CD262 PAb ALEXA FLUOR 350

Long name

TRAILR2/DR5 Antibody, ALEXA FLUOR 350 Conjugated

Source

KLH conjugated synthetic peptide derived from mouse DR5

Specificity

This is a highly specific antibody against TRAILR2/DR5/CD262.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

MK; DR5; Ly98; KILLER; TRICKB; TRAILR2; TRICK2A; TRICK2B; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; CD262; Tnfrsf10b

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).