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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Notch 2 Antibody, ALEXA FLUOR 594

Description:

Size: 100ul

Catalog no.: bs-2378R-A594

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Gene ID Number

4853

Modification Site

None

Swiss Prot

Q04721

Target Antigen

Notch 2

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Subcellular location

Extracellular

Immunogen range

1570-1620/2471

Conjugated

Alexa conjugate 1

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 594

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Notch 2 PAb ALEXA FLUOR 594

Specificity

This is a highly specific antibody against Notch 2.

Long name

Notch 2 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated

Synonyms

hN2; AGS2; HJCYS; Neurogenic locus notch homolog protein 2; Notch 2; NOTCH2

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Notch2

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation.