Description:

    Size: 100ul

    Catalog no.: bs-0654R-A488

    Price: 380 EUR

    Product details

    Target Antigen

    GHR

    Gene ID Number

    2690

    Modification Site

    None

    Swiss Prot

    P10912

    French translation

    anticorps

    Subcellular location

    Cytoplasm

    Tested applications

    IF(IHC-P)

    Clonality

    Polyclonal

    Modification

    Unmodified

    Excitation emission

    499nm/519nm

    Immunogen range

    290-340/638

    Concentration

    1ug per 1ul

    Conjugation

    Alexa Fluor

    Conjugated with

    ALEXA FLUOR® 488

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Crossreactivity

    Human, Mouse, Rat, Pig

    Purification

    Purified by Protein A.

    Also known as

    Anti-GHR PAb ALEXA FLUOR 488

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Specificity

    This is a highly specific antibody against GHR.

    Long name

    GHR Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

    Synonyms

    GHBP; Growth hormone receptor; GH receptor; Somatotropin receptor; GHR

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GHR

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Background of the antigen

    Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-GHR has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.