Description:

Size: 100ul

Catalog no.: bs-13248R-A350

Price: 380 EUR

Product details

Gene ID Number

2769

Modification Site

None

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Modification

Unmodified

Concentration

1ug per 1ul

Excitation emission

343nm/442nm

Conjugated with

ALEXA FLUOR® 350

Crossreactivity

Human, Mouse, Rat

Target Antigen

G protein alpha 16

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-G protein alpha 16 PAb ALEXA FLUOR 350

Specificity

This is a highly specific antibody against G protein alpha 16.

Long name

G protein alpha 16 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Description

The Anti-G protein alpha 16 is a α- or alpha protein sometimes glycoprotein present in blood.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G protein alpha 16

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Synonyms

G alpha 15; G alpha 16; G alpha-15; G alpha-16; G-protein subunit alpha-15; G-protein subunit alpha-16; GNA 15; GNA 16; GNA15; GNA15_HUMAN; GNA16; Gq class; Guanine nucleotide binding protein alpha 15; Guanine nucleotide binding protein alpha 15 subunit; Guanine nucleotide-binding protein subunit alpha-15; Guanine nucleotide-binding protein subunit alpha-16.

Background of the antigen

Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e., adenylyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, Beta and Gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of G alpha subunits have been identified; these include Gs, Gi, Gq and Ga 12/13 (3,4). The Gi class comprises all the known a subunits that are susceptible to pertussis toxin modifications, including Ga i-1, Ga i-2, Ga i-3, Ga o, Ga t1, Ga t2, Ga z and Ga gust (4). Of these, the three Ga i subtypes function to open atrial potassium channels (6). Ga 16 is a member of the Gq subfamily and is expressed specifically in hematopoietic cells (7).