Description:

Size: 100ul

Catalog no.: bs-0930R-A647

Price: 350 EUR

Product details

Gene ID Number

34119

Modification Site

Tyr43

Target Antigen

HP1 Tyr43

Tested applications

IF(IHC-P)

Cross-reactive species details

Fruit Fly

French translation

anticorps

Clonality

Polyclonal

Excitation emission

650nm/665nm

Concentration

1ug per 1ul

Crossreactivity

Other Species

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 647

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-HP1 Tyr43 PAb ALEXA FLUOR 647

Specificity

This is a highly specific antibody against HP1 Tyr43.

Long name

HP1(Tyr43) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

Synonyms

Heterochromatin protein 1; HP1; Non-histone chromosomal protein C1A9 antigen; CG8409

Source

KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-HP1 Tyr43 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.