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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / HDAC4(Ser246)/HDAC5(Ser259)/HDAC7(Ser155) Antibody, ALEXA FLUOR 647

Description:

Size: 100ul

Catalog no.: bs-3073R-A647

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Gene ID Number

9759

Modification Site

Ser155

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Excitation emission

650nm/665nm

Concentration

1ug per 1ul

Modification

Phosphorylation

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 647

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155

Also known as

Anti-HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155 PAb ALEXA FLUOR 647

Long name

HDAC4(Ser246)/HDAC5(Ser259)/HDAC7(Ser155) Antibody, ALEXA FLUOR 647 Conjugated

Specificity

This is a highly specific antibody against HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser246

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

HDAC4Ser246; HDAC5Ser259; HDAC7Ser155; HD 4; HD4; HDAC 4; HDAC A; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288; EC 3.5.1.98; HA6116; p-HDAC4Ser246; p-HDAC5Ser259; p-HDAC7Ser155.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-HDAC4 Ser246/HDAC5 Ser259/HDAC7 Ser155 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].