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    Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / PKC alpha/beta/gamma Antibody, ALEXA FLUOR 594

    Description:

    Size: 100ul

    Catalog no.: bs-3531R-A594

    Price: 380 EUR

    Get for 380 EUR on Gentaur.com

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    Product details

    Gene ID Number

    5578

    Modification Site

    None

    Swiss Prot

    P17252

    Tested applications

    IF(IHC-P)

    French translation

    anticorps

    Modification

    Unmodified

    Clonality

    Polyclonal

    Excitation emission

    590nm/617nm

    Concentration

    1ug per 1ul

    Immunogen range

    180-237/672

    Conjugated with

    ALEXA FLUOR® 594

    Conjugated

    Alexa conjugate 1

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Target Antigen

    PKC alpha/beta/gamma

    Crossreactivity

    Human, Mouse, Rat, Dog

    Purification

    Purified by Protein A.

    Conjugation

    Alexa Fluor,ALEXA FLUOR® 594

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-PKC alpha/beta/gamma PAb ALEXA FLUOR 594

    Subcellular location

    Cytoplasm, Nucleus, Mitochondrion, Cell membrane

    Specificity

    This is a highly specific antibody against PKC alpha/beta/gamma.

    Long name

    PKC alpha/beta/gamma Polyclonal Antibody, ALEXA FLUOR 594 Conjugated

    Synonyms

    AAG6; PKCA; PRKACA; PKC-alpha; Protein kinase C alpha type; PKC-A; PRKCA

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Description

    The Anti-PKC alpha/beta/gamma is a α- or alpha protein sometimes glycoprotein present in blood.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PKC alpha

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Properties

    For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.