Description:

Size: 100ul

Catalog no.: bs-3779R-A488

Price: 380 EUR

Product details

Gene ID Number

8338

Modification Site

None

Swiss Prot

Q16777

Subcellular location

Nucleus

French translation

anticorps

Immunogen range

10-60/130

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Modification

Unmodified

Target Antigen

Histone H2A

Excitation emission

499nm/519nm

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Histone H2A PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against Histone H2A.

Long name

Histone H2A Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

H2A; H2A/q; H2AFQ; H2A-GL101; Histone H2A type 2-C; Histone H2A-GL101; Histone H2A/q; HIST2H2AC

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone H2A

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Histone H2A has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.