Description:

Size: 100ul

Catalog no.: bs-4203R-A488

Price: 380 EUR

Product details

Gene ID Number

9826

Modification Site

None

Swiss Prot

O15085

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Target Antigen

PDZ RHOGEF

Modification

Unmodified

Excitation emission

499nm/519nm

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Immunogen range

1030-1080/1522

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Subcellular location

Cytoplasm, Membrane bound

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-PDZ RHOGEF PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against PDZ RHOGEF.

Long name

PDZ RHOGEF Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Synonyms

GTRAP48; PDZ-RHOGEF; Rho guanine nucleotide exchange factor 11; ARHGEF11; KIAA0380

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-PDZ RHOGEF has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.