Description:

    Size: 100ul

    Catalog no.: bs-10287R-A647

    Price: 380 EUR

    Product details

    Modification Site

    None

    Gene ID Number

    23645

    Swiss Prot

    O75807

    Target Antigen

    GADD34

    French translation

    anticorps

    Subcellular location

    Cytoplasm

    Clonality

    Polyclonal

    Modification

    Unmodified

    Excitation emission

    650nm/665nm

    Immunogen range

    415-450/674

    Concentration

    1ug per 1ul

    Tested applications

    FCM, IF(IHC-P)

    Crossreactivity

    Human, Mouse, Rat

    Conjugated with

    ALEXA FLUOR® 647

    Clone

    Polyclonal antibody

    Purification

    Purified by Protein A.

    Conjugation

    Alexa Fluor,ALEXA FLUOR 647

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-GADD34 PAb ALEXA FLUOR 647

    Recommended dilutions

    FCM(1:20-100), IF(IHC-P)(1:50-200)

    Specificity

    This is a highly specific antibody against GADD34.

    Long name

    GADD34 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GADD34

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Synonyms

    GADD34; Protein phosphatase 1 regulatory subunit 15A; Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116 homolog; PPP1R15A

    Background of the antigen

    Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-GADD34 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.