Description:

Size: 100ul

Catalog no.: bs-13196R-A488

Price: 380 EUR

Product details

Gene ID Number

2356

Modification Site

None

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Excitation emission

499nm/519nm

Conjugation

Alexa Fluor

Concentration

1ug per 1ul

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

FPGS/Folylpolyglutamate synthase

Also known as

Anti-FPGS/Folylpolyglutamate synthase PAb ALEXA FLUOR 488

Long name

Folylpolyglutamate synthase Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against FPGS/Folylpolyglutamate synthase.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FPGS/Folylpolyglutamate synthase

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

EC 6.3.2.17; FOLC; FOLC_HUMAN; Folylpoly gamma glutamate synthetase; Folylpoly-gamma-glutamate synthetase; Folylpolyglutamate synthase; Folylpolyglutamate synthase mitochondrial; FPGS; mitochondrial; OTTHUMP00000022201; OTTHUMP00000022202; Tetrahydrofolate synthase; Tetrahydrofolylpolyglutamate synthase.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-FPGS/Folylpolyglutamate synthase has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008].