Description:

Size: 100ul

Catalog no.: bs-2636R-A555

Price: 380 EUR

Product details

Modification Site

None

Gene ID Number

16399

Swiss Prot

Q9QUM0

Tested applications

IF(IHC-P)

Modification

Unmodified

Clonality

Polyclonal

Excitation emission

553nm/568nm

Concentration

1ug per 1ul

Immunogen range

370-420/1033

Subcellular location

Extracellular

Conjugated with

ALEXA FLUOR® 555

Crossreactivity

Human, Mouse, Rat

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Target Antigen

Integrin alpha 2b/CD41

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Integrin alpha 2b/CD41 PAb ALEXA FLUOR 555

Long name

Integrin alpha 2bPolyclonal Antibody, ALEXA FLUOR 555 Conjugated

Specificity

This is a highly specific antibody against Integrin alpha 2b/CD41.

Source

KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Description

The Anti-Integrin alpha 2b/CD41 is a α- or alpha protein sometimes glycoprotein present in blood.

Synonyms

CD41; CD41B; GpIIb; AI172977; alphaIIb; Integrin alpha-IIb; GPalpha IIb; Platelet membrane glycoprotein IIb; Itga2b

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.