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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / PKC alpha/beta II (Thr638/641) Antibody, ALEXA FLUOR 647

Description:

Size: 100ul

Catalog no.: bs-3333R-A647

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Gene ID Number

5578

Swiss Prot

P17252

Subcellular location

Cytoplasm

Tested applications

IF(IHC-P)

French translation

anticorps

Modification Site

Thr638/641

Clonality

Polyclonal

Excitation emission

650nm/665nm

Concentration

1ug per 1ul

Immunogen range

606-641/672

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 647

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Crossreactivity

Human, Mouse, Rat, Dog

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Target Antigen

PKC alpha/beta II Thr638/641

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-PKC alpha/beta II Thr638/641 PAb ALEXA FLUOR 647

Long name

PKC alpha/beta II (Thr638/641) Antibody, ALEXA FLUOR 647 Conjugated

Synonyms

AAG6; PKCA; PRKACA; PKC-alpha; Protein kinase C alpha type; PKC-A; PRKCA

Specificity

This is a highly specific antibody against PKC alpha/beta II Thr638/641.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Description

The Anti-PKC alpha/beta II Thr638/641 is a α- or alpha protein sometimes glycoprotein present in blood.

Source

KLH conjugated synthetic phosphopeptide derived from human PKC alpha/beta II around the phosphorylation site of Thr638/641

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-PKC alpha/beta II Thr638/641 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.