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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / NMDAR2B (Tyr1336) Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bs-5381R-A488

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Gene ID Number

2904

Swiss Prot

Q13224

Modification Site

Tyr1336

French translation

anticorps

Subcellular location

Cytoplasm

Clonality

Polyclonal

Conjugation

Alexa Fluor

Concentration

1ug per 1ul

Excitation emission

499nm/519nm

Immunogen range

1310-1360/1484

Tested applications

FCM, IF(IHC-P)

Modification

Phosphorylation

Target Antigen

NMDAR2B Tyr1336

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200)

Also known as

Anti-NMDAR2B Tyr1336 PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against NMDAR2B Tyr1336.

Long name

NMDAR2B (Tyr1336) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1336

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

MRD6; NR2B; hNR3; GluN2B; NMDAR2B; Glutamate receptor ionotropic, NMDA 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NR3; GRIN2B

Background of the antigen

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-NMDAR2B Tyr1336 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.