0208080893 nl@gentaur.com
    Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / MSK1 (Thr581) Antibody, ALEXA FLUOR 555

    Description:

    Size: 100ul

    Catalog no.: bs-3284R-A555

    Price: 350 EUR

    Get for 350 EUR on Gentaur.com

    /ningbo-assets-bio/graphics/prods/bigs/bigs12.jpg

    Product details

    Gene ID Number

    9252

    Modification Site

    Thr581

    Tested applications

    IF(IHC-P)

    French translation

    anticorps

    Clonality

    Polyclonal

    Target Antigen

    MSK1 Thr581

    Excitation emission

    553nm/568nm

    Concentration

    1ug per 1ul

    Crossreactivity

    Human, Mouse

    Modification

    Phosphorylation

    Conjugated with

    ALEXA FLUOR® 555

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Clone

    Polyclonal antibody

    Purification

    Purified by Protein A.

    Conjugation

    Alexa Fluor,ALEXA FLUOR 555

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-MSK1 Thr581 PAb ALEXA FLUOR 555

    Specificity

    This is a highly specific antibody against MSK1 Thr581.

    Long name

    MSK1 (Thr581) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    KLH conjugated synthetic phosphopeptide derived from human MSK1 around the phosphorylation site of Thr581 [LK(p-T)PC]

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Properties

    For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Synonyms

    MSK1 Phospho Thr581; 90 kDa ribosomal protein S6 kinase 5; EC 2.7.11.1; KS6A5_HUMAN; MGC1911; Mitogen and stress activated protein kinase 1; MSPK1; Nuclear Mitogen And Stress Activated Protein Kinase 1; Nuclear mitogen- and stress-activated protein kinase 1; Ribosomal protein S6 kinase 90kD polypeptide 5; Ribosomal protein S6 kinase 90kDa; Ribosomal protein S6 kinase 90kDa polypeptide 5; Ribosomal Protein S6 Kinase Alpha 5; Ribosomal protein S6 kinase alpha-5; RLPK; RPS6KA5; RSK Like Protein Kinase; RSK-like protein kinase; RSKL; S6K alpha 5; S6K-alpha-5.

    Background of the antigen

    MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.