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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Rictor (Thr1135) Antibody, ALEXA FLUOR 555

Description:

Size: 100ul

Catalog no.: bs-3387R-A555

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Gene ID Number

253260

Swiss Prot

Q6R327

Modification Site

Thr1135

French translation

anticorps

Subcellular location

Cytoplasm

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Concentration

1ug per 1ul

Excitation emission

553nm/568nm

Crossreactivity

Human, Mouse

Target Antigen

Rictor Thr1135

Immunogen range

1100-1150/1732

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 555

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Rictor Thr1135 PAb ALEXA FLUOR 555

Specificity

This is a highly specific antibody against Rictor Thr1135.

Long name

Rictor (Thr1135) Polyclonal Antibody, ALEXA FLUOR 555 Conjugated

Synonyms

PIA; AVO3; hAVO3; Rapamycin-insensitive companion of mTOR; AVO3 homolog; RICTOR; KIAA1999

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human Rictor around the phosphorylation site of Thr1135

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development.