Description:

    Size: 100ul

    Catalog no.: bs-3333R-A555

    Price: 350 EUR

    Product details

    Gene ID Number

    5578

    Swiss Prot

    P17252

    Subcellular location

    Cytoplasm

    Tested applications

    IF(IHC-P)

    French translation

    anticorps

    Modification Site

    Thr638/641

    Clonality

    Polyclonal

    Excitation emission

    553nm/568nm

    Concentration

    1ug per 1ul

    Immunogen range

    606-641/672

    Modification

    Phosphorylation

    Conjugated with

    ALEXA FLUOR® 555

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Purification

    Purified by Protein A.

    Crossreactivity

    Human, Mouse, Rat, Dog

    Conjugation

    Alexa Fluor,ALEXA FLUOR 555

    Target Antigen

    PKC alpha/beta II Thr638/641

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-PKC alpha/beta II Thr638/641 PAb ALEXA FLUOR 555

    Long name

    PKC alpha/beta II (Thr638/641) Antibody, ALEXA FLUOR 555 Conjugated

    Synonyms

    AAG6; PKCA; PRKACA; PKC-alpha; Protein kinase C alpha type; PKC-A; PRKCA

    Specificity

    This is a highly specific antibody against PKC alpha/beta II Thr638/641.

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Description

    The Anti-PKC alpha/beta II Thr638/641 is a α- or alpha protein sometimes glycoprotein present in blood.

    Source

    KLH conjugated synthetic phosphopeptide derived from human PKC alpha/beta II around the phosphorylation site of Thr638/641

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Properties

    For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    Protein Kinase c alpha (PKC alpha) is an 77 kDa member of the conventional group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine and phorbol esters) of the PKC family of serine/ threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC alpha is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of a broad range of cellular functions including proliferation, differentiation, development, migration, cell cell adhesion, cell extracellular matrix adhesion, and solute transport. The activation loop threonine (threonine 497 in PKC alpha) of conventional PKCs is phosphorylated by phosphoinositide dependent kinase 1 (PDK1). This phosphorylation is necessary for the autophosphorylation of threonine 638 in the carboxy terminus of PKC alpha, a step that is critical for regulating the rate of PKC alpha dephosphorylation and inactivation.