0208080893 nl@gentaur.com
    Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / RFC1 Antibody, ALEXA FLUOR 488

    Description:

    Size: 100ul

    Catalog no.: bs-11304R-A488

    Price: 380 EUR

    Get for 380 EUR on Gentaur.com

    /ningbo-assets-bio/graphics/prods/bigs/bigs3.jpg

    Product details

    Gene ID Number

    5981

    Modification Site

    None

    Target Antigen

    RFC1

    Swiss Prot

    P35251

    Subcellular location

    Nucleus

    French translation

    anticorps

    Tested applications

    IF(IHC-P)

    Clonality

    Polyclonal

    Modification

    Unmodified

    Excitation emission

    499nm/519nm

    Concentration

    1ug per 1ul

    Conjugation

    Alexa Fluor

    Immunogen range

    420-465/1148

    Crossreactivity

    Human, Mouse, Rat

    Conjugated with

    ALEXA FLUOR® 488

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Purification

    Purified by Protein A.

    Also known as

    Anti-RFC1 PAb ALEXA FLUOR 488

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Specificity

    This is a highly specific antibody against RFC1.

    Long name

    RFC1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RFC1

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Synonyms

    A1; RFC; PO-GA; RECC1; MHCBFB; RFC140; Replication factor C subunit 1; Activator 1 140 kDa subunit; A1 140 kDa subunit; Activator 1 large subunit; Activator 1 subunit 1; DNA-binding protein PO-GA; Replication factor C 140 kDa subunit; RF-C 140 kDa subunit; Replication factor C large subunit; RFC1

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-RFC1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.