Description:

Size: 100ul

Catalog no.: bs-12955R-A594

Price: 350 EUR

Product details

Crossreactivity

Human

Modification Site

Ser1263

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

Acetyl Coenzyme A Carboxylase alpha Ser1263

Also known as

Anti-Acetyl Coenzyme A Carboxylase alpha Ser1263 PAb ALEXA FLUOR 594

Long name

Acetyl Coenzyme A Carboxylase alpha (Ser1263) Antibody, ALEXA FLUOR 594 Conjugated

Specificity

This is a highly specific antibody against Acetyl Coenzyme A Carboxylase alpha Ser1263.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase alpha around the phosphorylation site of Ser1263

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

N terminal acetylation or CH3CO as epigenetic regulation of Anti-Acetyl Coenzyme A Carboxylase alpha Ser1263 by NATs.The Anti-Acetyl Coenzyme A Carboxylase alpha Ser1263 is a α- or alpha protein sometimes glycoprotein present in blood.

Synonyms

Acetyl Coenzyme A Carboxylase alpha phospho S1263; p-Acetyl Coenzyme A Carboxylase alpha phospho S1263; ACAC; ACACA; ACACA; ACACA_HUMAN; ACC alpha; ACC; ACC-alpha; ACC1; ACC1; ACCA; acetyl CoA carboxylase 1; acetyl Coenzyme A; Acetyl Coenzyme A; Biotin carboxylase; Acetyl-Coenzyme A Carboxylase alpha.

Background of the antigen

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].