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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / MEK1/2(Ser218 + Ser222) Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bs-3270R-A488

Price: 350 EUR

Get for 350 EUR on Gentaur.com

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Product details

Gene ID Number

56045605

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Conjugation

Alexa Fluor

Concentration

1ug per 1ul

Immunogen range

180-230/393

Excitation emission

499nm/519nm

Modification

Phosphorylation

Modification Site

Ser218 + Ser222

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Subcellular location

Cytoplasm, Nucleus

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Target Antigen

MEK1/2 Ser218 + Ser222

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-MEK1/2 Ser218 + Ser222 PAb ALEXA FLUOR 488

Long name

MEK1/2(Ser218 + Ser222) Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against MEK1/2 Ser218 + Ser222.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Ser218/222

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

MAP2K1phospho S218/S222; Dual specicity mitogen activated protein kinase kinase 1; ERK activator kinase 1; MAP kinase kinase 1; MAP kinase/Erk kinase 1; MAP/Erk kinase 1; Map2K1; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; MEKK1; Mitogen activated protein kinase kinase 1; MKK 1; MKK1; PRKMK 1; PRKMK1;Protein kinase mitogen activated kinase 1 MAP kinase kinase 1; Protein kinase mitogen activated kinase 1; Protein kinase mitogen activated, kinase 1.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-MEK1/2 Ser218 + Ser222 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.