Description:

Size: 100ul

Catalog no.: bs-6136R-A488

Price: 380 EUR

Product details

Modification Site

None

Crossreactivity

Virus

Swiss Prot

P03255

Subcellular location

Nucleus

French translation

anticorps

Tested applications

IF(IHC-P)

Virus

adenovirus

Clonality

Polyclonal

Modification

Unmodified

Concentration

1ug per 1ul

Immunogen range

180-230/289

Excitation emission

499nm/519nm

Conjugation

Alexa Fluor

Cross-reactive species details

Adenovirus5

Target Antigen

Adenovirus 5 E1A

Conjugated with

ALEXA FLUOR® 488

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Adenovirus 5 E1A PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against Adenovirus 5 E1A.

Long name

Adenovirus 5 E1A Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Adenovirus 5 E1A

Synonyms

Adenovirus early E1A protein; Control protein E1A; E1A; Early E1A protein; Human adenovirus type 5; Human adenovirus C; pfam02703; E1A_ADE05.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Adenovirus 5 E1A has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.