Description:

Size: 100ul

Catalog no.: bs-12402R-A488

Price: 380 EUR

Product details

Modification Site

None

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Target Antigen

RBM15/SPEN

Modification

Unmodified

Excitation emission

499nm/519nm

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-RBM15/SPEN PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against RBM15/SPEN.

Long name

RBM15/SPEN Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Synonyms

One twenty two protein; OTT; OTT1; SPEN; RNA binding mot protein 15; RBM15_HUMAN.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RBM15

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-RBM15/SPEN has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia.