Description:

    Size: 100ul

    Catalog no.: bs-2378R-A350

    Price: 380 EUR

    Product details

    Gene ID Number

    4853

    Modification Site

    None

    Swiss Prot

    Q04721

    Target Antigen

    Notch 2

    French translation

    anticorps

    Tested applications

    IF(IHC-P)

    Clonality

    Polyclonal

    Modification

    Unmodified

    Excitation emission

    343nm/442nm

    Concentration

    1ug per 1ul

    Subcellular location

    Extracellular

    Immunogen range

    1570-1620/2471

    Crossreactivity

    Human, Mouse, Rat

    Conjugated with

    ALEXA FLUOR® 350

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Purification

    Purified by Protein A.

    Conjugation

    Alexa Fluor,ALEXA FLUOR 350

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-Notch 2 PAb ALEXA FLUOR 350

    Specificity

    This is a highly specific antibody against Notch 2.

    Long name

    Notch 2 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

    Synonyms

    hN2; AGS2; HJCYS; Neurogenic locus notch homolog protein 2; Notch 2; NOTCH2

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Notch2

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation.