Description:

Size: 100ul

Catalog no.: bs-10489R-A488

Price: 380 EUR

Product details

Virus

hhv

Modification Site

None

Cross-reactive species details

HHV1

Crossreactivity

Virus

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Excitation emission

499nm/519nm

Immunogen range

1200-1235/1235

Conjugated with

ALEXA FLUOR® 488

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

HHV DNA polymerase catalytic subunit

Also known as

Anti-HHV DNA polymerase catalytic subunit PAb ALEXA FLUOR 488

Synonyms

DPOL_HHV11; DNA polymerase catalytic subunit; UL30; HHV1gp046.

Long name

HHV DNA polymerase catalytic subunit Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against HHV DNA polymerase catalytic subunit.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-HHV DNA polymerase catalytic subunit has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.