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    Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Apaf1 Interacting Protein Antibody, ALEXA FLUOR 594

    Description:

    Size: 100ul

    Catalog no.: bs-6792R-A594

    Price: 380 EUR

    Get for 380 EUR on Gentaur.com

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    Product details

    Modification Site

    None

    Gene ID Number

    51074

    Tested applications

    IF(IHC-P)

    French translation

    anticorps

    Modification

    Unmodified

    Clonality

    Polyclonal

    Concentration

    1ug per 1ul

    Excitation emission

    590nm/617nm

    Conjugated with

    ALEXA FLUOR® 594

    Crossreactivity

    Human, Mouse, Rat

    Conjugated

    Alexa conjugate 1

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Clone

    Polyclonal antibody

    Purification

    Purified by Protein A.

    Target Antigen

    Apaf1 Interacting Protein

    Category

    Conjugated Primary Antibodies

    Conjugation

    Alexa Fluor,ALEXA FLUOR® 594

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-Apaf1 Interacting Protein PAb ALEXA FLUOR 594

    Long name

    Apaf1 Interacting Protein Antibody, ALEXA FLUOR 594 Conjugated

    Specificity

    This is a highly specific antibody against Apaf1 Interacting Protein.

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APIP

    Synonyms

    MTNB_HUMAN; Apaf1 Interacting Protein; APIP2; CG129; CGI 29; MMRP19; MTRu 1 P dehydratase; Probable methylthioribulose 1 phosphate dehydratase.

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Properties

    For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    The mammalian homologues of the key cell death gene CED 4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), which leads to caspase 9 activation. Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, has been identified as a negative regulator of ischemic injury. APIP competes with Caspase 9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney.