Description:

    Size: 100ul

    Catalog no.: bs-13354R-A488

    Price: 380 EUR

    Product details

    Gene ID Number

    2689

    Modification Site

    None

    Crossreactivity

    Human

    Tested applications

    IF(IHC-P)

    French translation

    anticorps

    Modification

    Unmodified

    Clonality

    Polyclonal

    Excitation emission

    499nm/519nm

    Conjugation

    Alexa Fluor

    Concentration

    1ug per 1ul

    Conjugated with

    ALEXA FLUOR® 488

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Clone

    Polyclonal antibody

    Target Antigen

    GH2/Growth hormone 2

    Purification

    Purified by Protein A.

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-GH2/Growth hormone 2 PAb ALEXA FLUOR 488

    Specificity

    This is a highly specific antibody against GH2/Growth hormone 2.

    Long name

    GH2/Growth hormone 2 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GH2/Growth hormone 2

    Synonyms

    GH 2; GH V; GH2; GHL; GHV; Growth hormone 2; Growth hormone variant; hGH V; hGHV; Placenta specic growth hormone; Placental specic growth hormone; SOM2_HUMAN.

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Description

    Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-GH2/Growth hormone 2 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    Growth hormone 2 (GH2) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. The major role of GH2 in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.