Description:

Size: 100ul

Catalog no.: bs-5856R-A350

Price: 380 EUR

Product details

Modification Site

None

Gene ID Number

11093

Subcellular location

Secreted

Target Antigen

ADAMTS13

French translation

anticorps

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

343nm/442nm

Concentration

1ug per 1ul

Tested applications

FCM, IF(IHC-P)

Conjugated with

ALEXA FLUOR® 350

Crossreactivity

Human, Mouse, Rat

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-ADAMTS13 PAb ALEXA FLUOR 350

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200)

Specificity

This is a highly specific antibody against ADAMTS13.

Long name

ADAMTS13 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAMTS13

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Synonyms

Cleaves the vWF multimers in plasma into smaller forms. Von Willebrand factor cleaving protease; A disintegrin and metalloproteinase with thrombospondin mots 13; A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot 13; A disintegrin like and metalloprotease with thrombospondin type 1 mot 13; ADAM metallopeptidase with thrombospondin type 1 mot 13; ADAM TS 13; ADAM TS13; ADAM-TS 13; ADAM-TS13; ADAMTS 13; ADAMTS-13; ADAMTS13; ADAMTS13 protein; ATS13_HUMAN; C9orf8; TTP; von Willebrand factor-cleaving protease; vWF cleaving protease; vWF CP; vWF-cleaving protease; vWF-CP; vWFCP.

Background of the antigen

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].