Description:

Size: 100ul

Catalog no.: bs-13188R-A647

Price: 350 EUR

Product details

Gene ID Number

2332

Swiss Prot

Q06787

Modification Site

Ser500

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Concentration

1ug per 1ul

Immunogen range

480-530/632

Excitation emission

650nm/665nm

Target Antigen

FMRP Ser500

Modification

Phosphorylation

Conjugated with

ALEXA FLUOR® 647

Crossreactivity

Human, Mouse, Rat

Subcellular location

Cytoplasm, Nucleus

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-FMRP Ser500 PAb ALEXA FLUOR 647

Specificity

This is a highly specific antibody against FMRP Ser500.

Long name

FMRP (Ser500) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

Synonyms

POF; FMRP; POF1; FRAXA; Fragile X mental retardation protein 1; Protein FMR-1; FMR1

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Background of the antigen

Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-FMRP Ser500 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.