Description:

    Size: 100ul

    Catalog no.: bs-3393R-A350

    Price: 350 EUR

    Product details

    Gene ID Number

    23411

    Modification Site

    Ser47

    Swiss Prot

    Q96EB6

    French translation

    anticorps

    Immunogen range

    20-60/747

    Tested applications

    IF(IHC-P)

    Clonality

    Polyclonal

    Concentration

    1ug per 1ul

    Excitation emission

    343nm/442nm

    Target Antigen

    SIRT1 Ser47

    Crossreactivity

    Human, Mouse

    Modification

    Phosphorylation

    Conjugated with

    ALEXA FLUOR® 350

    Subcellular location

    Cytoplasm, Nucleus

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Purification

    Purified by Protein A.

    Conjugation

    Alexa Fluor,ALEXA FLUOR 350

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-SIRT1 Ser47 PAb ALEXA FLUOR 350

    Specificity

    This is a highly specific antibody against SIRT1 Ser47.

    Long name

    SIRT1(Ser47) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    KLH conjugated synthetic phosphopeptide derived from human SirT1 around the phosphorylation site of Ser47

    Synonyms

    SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2; SIRT1

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.