Background of the antigen
Olfactory receptors are G protein-coupled receptors that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction that propagates nerve impulses throughout the body, ultimately leading to transmission of the signal to the brain and the subsequent perception of smell. OR10J3 (olfactory receptor 10J3) is a 329 amino acid protein. The gene encoding OR10J3 maps to human chromosome 1.
