Description:

Size: 100ul

Catalog no.: bs-11884R-A488

Price: 380 EUR

Product details

Modification Site

None

French translation

anticorps

Tested applications

IF(IHC-P)

Clonality

Polyclonal

Modification

Unmodified

Concentration

1ug per 1ul

Conjugation

Alexa Fluor

Excitation emission

499nm/519nm

Target Antigen

MATH2/NEUROD6

Conjugated with

ALEXA FLUOR® 488

Crossreactivity

Human, Mouse, Rat

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-MATH2/NEUROD6 PAb ALEXA FLUOR 488

Specificity

This is a highly specific antibody against MATH2/NEUROD6.

Long name

MATH2/NEUROD6 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MATH2/NEUROD6

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

Atoh 2; Atoh2; Atonal homolog 2; Atonal protein homolog 2; Atonal protein homolog2; bHLH a2 antibodybHLHa 2; bHLHa2; Class A basic helix-loop-helix protein 2; Helix loop helix protein mATH 2; Helix loop helix protein mATH2; MATH 2; Math2; NDF 6; NDF6; NDF6_HUMAN; Neuro D6; NeuroD6; Neurogenic dferentiation 6; Neurogenic dferentiation factor 6; Nex 1 antibodyNex 1m; Nex; Nex1; Nex1 m; Nex1m; Protein atonal homolog 2; Protein atonal homolog2.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-MATH2/NEUROD6 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 2 (MATH-2) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of Drosophila atonal gene. MATH-2 is a 337 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-2 takes place by embryonic day 11.5 and initially localizes to the wall of brain vesicles and in the spinal cord. It is expressed in the cortical plate and the mantle layer in the developing central nervous system, and is limited to the nervous system in adults. Adult mouse cerebrums produce a high level of MATH-2 RNA with lower levels in other neuronal tissues. Research studies suggest that MATH-2 may function as a trans-acting factor involved in the development and maintenance of the mammalian nervous system.