Description:

    Size: 100ul

    Catalog no.: bs-4636R-A350

    Price: 380 EUR

    Product details

    Gene ID Number

    7182

    Modification Site

    None

    Swiss Prot

    P49116

    Subcellular location

    Nucleus

    French translation

    anticorps

    Tested applications

    IF(IHC-P)

    Target Antigen

    NR2C2/TAK1

    Clonality

    Polyclonal

    Modification

    Unmodified

    Excitation emission

    343nm/442nm

    Immunogen range

    490-540/596

    Concentration

    1ug per 1ul

    Crossreactivity

    Human, Mouse, Rat

    Conjugated with

    ALEXA FLUOR® 350

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Purification

    Purified by Protein A.

    Conjugation

    Alexa Fluor,ALEXA FLUOR 350

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-NR2C2/TAK1 PAb ALEXA FLUOR 350

    Specificity

    This is a highly specific antibody against NR2C2/TAK1.

    Long name

    NR2C2/TAK1 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NR2C2/TAK1

    Synonyms

    TR4; TAK1; Nuclear receptor subfamily 2 group C member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; Testicular receptor 4; NR2C2

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.