Description:

Size: 100ul

Catalog no.: bs-3776R-A594

Price: 350 EUR

Product details

Gene ID Number

3020

Swiss Prot

P84243

Subcellular location

Nucleus

Immunogen range

1-40/136

Modification Site

acetyl K9

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Modification

Acetylation

Excitation emission

590nm/617nm

Concentration

1ug per 1ul

Conjugated with

ALEXA FLUOR® 594

Crossreactivity

Human, Mouse, Rat

Conjugated

Alexa conjugate 1

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Target Antigen

Histone H3 acetyl K9

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Synonyms

H3F3; H3.3A; Histone H3.3; H3F3A; PP781

Also known as

Anti-Histone H3 acetyl K9 PAb ALEXA FLUOR 594

Long name

Histone H3 (acetyl K9) Antibody, ALEXA FLUOR 594 Conjugated

Specificity

This is a highly specific antibody against Histone H3 acetyl K9.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Description

N terminal acetylation or CH3CO as epigenetic regulation of Anti-Histone H3 acetyl K9 by NATs.

Source

KLH conjugated synthetic acetylpeptide derived from human Histone H3 around acetylation site of Lys9

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.