Description:

Size: 100ul

Catalog no.: bs-1894R-A555

Price: 380 EUR

Product details

Gene ID Number

2914

Modification Site

None

Swiss Prot

Q14833

French translation

anticorps

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

553nm/568nm

Immunogen range

340-381/912

Concentration

1ug per 1ul

Subcellular location

Extracellular

Tested applications

FCM, IF(IHC-P)

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 555

Clone

Polyclonal antibody

Purification

Purified by Protein A.

Conjugation

Alexa Fluor,ALEXA FLUOR 555

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200)

Target Antigen

Metabotropic Glutamate Receptor 4+6

Also known as

Anti-Metabotropic Glutamate Receptor 4+6 PAb ALEXA FLUOR 555

Synonyms

mGlu4; GPRC1D; MGLUR4; Metabotropic glutamate receptor 4; GRM4

Long name

Metabotropic Glutamate Receptor 4+6 Antibody, ALEXA FLUOR 555 Conjugated

Specificity

This is a highly specific antibody against Metabotropic Glutamate Receptor 4+6.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 4

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.Very high photo stable ALEXA conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.