Description:

Size: 100ul

Catalog no.: bs-0166R-A594

Price: 380 EUR

Product details

Gene ID Number

6870

Modification Site

None

Swiss Prot

P29371

Tested applications

IF(IHC-P)

French translation

anticorps

Clonality

Polyclonal

Modification

Unmodified

Excitation emission

590nm/617nm

Immunogen range

220-245/465

Concentration

1ug per 1ul

Subcellular location

Extracellular

Crossreactivity

Human, Mouse, Rat

Conjugated

Alexa conjugate 1

Conjugated with

ALEXA FLUOR® 594

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Target Antigen

Neurokinin B receptor

Purification

Purified by Protein A.

Category

Conjugated Primary Antibodies

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Host Organism

Rabbit (Oryctolagus cuniculus)

Also known as

Anti-Neurokinin B receptor PAb ALEXA FLUOR 594

Long name

Neurokinin B receptor Antibody, ALEXA FLUOR 594 Conjugated

Specificity

This is a highly specific antibody against Neurokinin B receptor.

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NKR

Synonyms

NKR; HH11; NK3R; NK-3R; TAC3RL; Neuromedin-K receptor; NK-3 receptor; Neurokinin B receptor; Tachykinin receptor 3; TACR3; TAC3R

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.