Description:

    Size: 100ul

    Catalog no.: bs-5242R-A488

    Price: 350 EUR

    Product details

    Gene ID Number

    993

    Modification Site

    Ser124

    Tested applications

    IF(IHC-P)

    French translation

    anticorps

    Clonality

    Polyclonal

    Conjugation

    Alexa Fluor

    Excitation emission

    499nm/519nm

    Concentration

    1ug per 1ul

    Target Antigen

    cdc25A Ser124

    Modification

    Phosphorylation

    Crossreactivity

    Human, Mouse, Rat

    Conjugated with

    ALEXA FLUOR® 488

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Clone

    Polyclonal antibody

    Purification

    Purified by Protein A.

    Category

    Conjugated Primary Antibodies

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Also known as

    Anti-cdc25A Ser124 PAb ALEXA FLUOR 488

    Specificity

    This is a highly specific antibody against cdc25A Ser124.

    Long name

    cdc25A (Ser124) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    KLH conjugated synthetic phosphopeptide derived from human cdc25A around the phosphorylation site of Ser124 [SH(p-S)DS]

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Synonyms

    Cdc 25a; CDC25A2; Cell division cycle 25 homolog A S. pombe; Cell division cycle 25A; Cell division cycle 25A isoform a; Cell division cycle 25A isoform bv D9Ertd393ev Dual specicity phosphatase CDC25A; EC 3.1.3.48; M phase inducer phosphatase 1; MGC115549; MPIP1_HUMAN.

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-cdc25A Ser124 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    Cyclin dependent kinases are positively regulated by association with cyclins and negatively regulated by binding to inhibitory subunits. The activity of cyclin dependent kinases is also regulated by the phosphorylation status, which is controlled by the antagonistic action of Wee1 kinase and CDC25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. Whereas CDC25A and CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A and in both G1 S phase and G2 for CDC25B, CDC25C is predominantly expressed in G2.