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    Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / RNF31 Antibody, ALEXA FLUOR 647

    Description:

    Size: 100ul

    Catalog no.: bs-9241R-A647

    Price: 380 EUR

    Get for 380 EUR on Gentaur.com

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    Product details

    Modification Site

    None

    Gene ID Number

    55072

    Target Antigen

    RNF31

    Swiss Prot

    Q96EP0

    Subcellular location

    Cytoplasm

    Tested applications

    IF(IHC-P)

    French translation

    anticorps

    Clonality

    Polyclonal

    Modification

    Unmodified

    Excitation emission

    650nm/665nm

    Concentration

    1ug per 1ul

    Crossreactivity

    Human, Mouse, Rat

    Conjugated with

    ALEXA FLUOR® 647

    Clone

    Polyclonal antibody

    Recommended dilutions

    IF(IHC-P)(1:50-200)

    Purification

    Purified by Protein A.

    Conjugation

    Alexa Fluor,ALEXA FLUOR 647

    Category

    Conjugated Primary Antibodies

    Also known as

    Anti-RNF31 PAb ALEXA FLUOR 647

    Host Organism

    Rabbit (Oryctolagus cuniculus)

    Specificity

    This is a highly specific antibody against RNF31.

    Long name

    RNF31 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

    Cross-reactive species details

    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

    Source

    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF31

    Storage conditions

    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

    Synonyms

    HOIP; ZIBRA; E3 ubiquitin-protein ligase RNF31; HOIL-1-interacting protein; RING finger protein 31; Zinc in-between-RING-finger ubiquitin-associated domain protein; RNF31

    Properties

    For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-RNF31 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

    Background of the antigen

    E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.