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Providers / Bioss Primary Conjugated Antibodies. ALEXA FLUOR / Endothelin-1(2C4) Monoclonal Antibody, ALEXA FLUOR 488

Description:

Size: 100ul

Catalog no.: bsm-0954M-A488

Price: 380 EUR

Get for 380 EUR on Gentaur.com

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Product details

Clone

2C4

Gene ID Number

1906

Modification Site

None

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Clonality

Monoclonal

Crossreactivity

Human, Rat

Excitation emission

499nm/519nm

Conjugation

Alexa Fluor

Concentration

1ug per 1ul

Target Antigen

Endothelin-1

Conjugated with

ALEXA FLUOR® 488

Recommended dilutions

IF(IHC-P)(1:50-200)

Host Organism

Mouse (Mus musculus)

Purification

Purified by Protein G.

Category

Conjugated Primary Antibodies

Also known as

Anti-Endothelin-1 MAb ALEXA FLUOR 488

Synonyms

EDN 1; EDN1; EDN1 protein; Endothelin1; ET 1; ET1;

Specificity

This is a highly specific antibody against Endothelin-1.

Long name

Endothelin-1(2C4) Monoclonal Antibody, ALEXA FLUOR 488 Conjugated

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Endothelin-1

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Background of the antigen

Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Endothelin-1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.